Vamp

VAMP - vesicle-associated membrane protein or synaptobrevin is a small integral membrane protein of secretory vesicle. Its molecular weight is approximately 18 kilodalton (kDa). In mammals, three VAMP isoforms have been described. VAMP-1 and -2 are brain-specific proteins whereas the third isoform, cellubrevin, is expressed ubiquitously.

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VAMP is one of the SNARE proteins involved in formation of the SNARE complexes. Out of four helices of a SNARE complex one is contributed by VAMP.

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SNARE proteins are believed to be the key components of the molecular machinery that drives fusion of membranes in e.g. exocytosis.

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Due to the fact that all proteins belonging to VAMP/Synaptobrevin family share common structural feature, they have been classified as R-SNAREs. An alternative classification (v- and t-SNAREs) exists that takes into account origin of VAMP-bearing organelle rather than their structural properties

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Integral membrane protein: An Integral Membrane Protein (IMP) is a protein molecule (or assembly of proteins) that in most cases spans the biological membrane with which it is associated (especially the plasma membrane) or which, in any case, is sufficiently embedded in the membrane to remain with it during the initial steps ...

Secretory vesicle: REDIRECT Secretion...

Kilodalton: REDIRECT Atomic mass unit...

Vamp related Images and Photos (experimental)

True Blood 'Baby Vamp' Women's T-Shirt

G.I. Joe VAMP Vehicle with Driver

Metal Gear Solid 4 Vamp Action Figure