U.S. Highway 50

United States Highway 50 is an east-west United States highway. As the "0" in its route number suggests, US 50 is a coast-to-coast route, or at least nearly so. Signs at both termini give the Maryland to California distance as 3,073 miles (4,946 km), though that mileage is based off of an older measurment and has likely changed due to bypasses, Interstate highway co-signings, and other realignments.

Alternate names and multiplexes

Maryland

• Known as Ocean Gateway from its eastern terminus to its multiplex with US 301
• Maryland State Highway 16 in Cambridge, Maryland
• U.S. Highway 301 from Queenstown, Maryland to Bowie, Maryland
• Blue Star Highway from the east end of the US 301 multiplex to Annapolis, Maryland
• Maryland State Highway 2 in Annapolis, Maryland
• Known as the John Hanson Highway from Annapolis, Maryland to Washington, DC
• Interstate 595 (unsigned) from Annapolis to the Capital Beltway in New Carrollton, Maryland

District of Columbia

• U.S. Highway 1 along Constitution Avenue (see Constitution Avenue article for a detailed explanation)
• Interstate 66 across the Theodore Roosevelt Bridge between Washington, D.C., and Arlington County, Virginia

Virginia, West Virginia

• Known as the Northwestern Turnpike from Winchester, Virginia to Parkersburg, West Virginia where it crosses the Ohio River.

Kansas

• Interstate 35 from Lenexa, Kansas to Emporia, Kansas

Nevada

• Known as the Loneliest Road in America in Nevada.
• In Nevada it follows closely the route of the Pony Express

California

• Known as the Lincoln Highway in California
• Known as the Capital City Freeway sharing the route with Business Loop Interstate 80 between I-80 in West Sacramento and California State Route 99 in Sacramento.