Transformation (genetics)

Transformation is the genetic alteration of a cell resulting from the introduction, uptake and expression of foreign genetic material (DNA or RNA).

Related Topics:
Cell - DNA - RNA

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This is a common technique in molecular biology. The effect was first demonstrated in 1944 by Oswald Avery, Collin Macleod, and Maclyn McCarty, who first demonstrated gene transfer in Streptococcus pneumoniae. Oswald, Macleod and McCarty call the uptake and incorporation of DNA by bacteria transformation.

Related Topics:
Molecular biology - 1944 - Oswald Avery - Collin Macleod - Maclyn McCarty - Gene - Streptococcus pneumoniae

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More generally the term is used to describe mechanisms of DNA and RNA transfer in

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molecular biology. For example the production of transgenic plants

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like transgenic maize requires the insertion of new

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genetic information into the maize genome using an appropriate

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mechanism for DNA transfer.

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