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Total synthesis


 

A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (often petrochemical) precursors. Total syntheses are often used as a playground for the development of new chemical reactions and routes.

Related Topics:
Chemical synthesis - Organic - Molecule - Petrochemical

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Classical examples are the total syntheses of quinine, cholesterol, cortisone, strychnine, lysergic acid, reserpine, chlorophyll, colchicine, vitamin B12, and prostaglandin F-2a by the Nobel Prize winner Robert B. Woodward between 1945 and 1976.

Related Topics:
Quinine - Cholesterol - Cortisone - Strychnine - Lysergic acid - Reserpine - Chlorophyll - Colchicine - Vitamin B12 - Prostaglandin F-2a - Nobel Prize - Robert B. Woodward

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Elias James Corey has won the Nobel Prize in Chemistry in 1990 for lifetime achievement in total synthesis and the development of retrosynthetic analysis.

Related Topics:
Elias James Corey - Nobel Prize in Chemistry - 1990 - Retrosynthetic analysis

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Today the group of Kyriacos Costa Nicolaou at the Scripps Research Institute is famous for their total syntheses.

Related Topics:
Kyriacos Costa Nicolaou - Scripps Research Institute

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