Spironolactone

Spironolactone (marketed as Aldactone or Spiritone) is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat low-renin hypertension, hypokalemia, and Conn's syndrome. On its own, spironolactone is only a weak diuretic, but it can be combined with other diuretics. Due to its anti-androgen effect, it can also be used to treat hirsutism, and is a common component in hormone therapy for male-to-female transgendered people.

Related Topics:
Lactone - Steroid - Aldosterone - Pharmaceutical - Potassium - Diuretic - Renin - Hypertension - Hypokalemia - Conn's syndrome - Androgen - Hirsutism - Hormone therapy - Transgender

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