Sharpless epoxidation

Sharpless epoxidation is a chemical reaction of an allylic alcohol with t-butylperoxide and titanium tetraisopropylate to form an epoxide. To form chiral products it is possible to add diethyltartrates.

Related Topics:
Chemical reaction - Epoxide - Chiral

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Epoxides can be easily converted into dialcohols, aminoalcohols or ethers, so formation of chiral epoxides is a very important step in the synthesis of natural products.

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K. Barry Sharpless shared the Nobel prize in 2001 for his work on asymmetric oxidations.

Related Topics:
K. Barry Sharpless - Nobel prize

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The prize was shared with William S. Knowles and Ryoji Noyori.

Related Topics:
William S. Knowles - Ryoji Noyori

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