Serotonin

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Serotonin

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Chemical name5-Hydroxy-tryptamine or3-(2-aminoethyl)-1H-indol-5-ol

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Chemical formulaC10H12N2O

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Molecular mass176.22 g/mol

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CAS number50-67-9

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SMILESNCCC1=CNC2=C1C=C(O)C=C2

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Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract.

Related Topics:
Monoamine - Neurotransmitter - Enterochromaffin

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Serotonin is believed to play an important part of the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite.

Related Topics:
Biochemistry - Depression - Migraine - Bipolar disorder - Anxiety - Sexuality - Appetite

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The name "serotonin" is something of a misnomer and reflects the circumstances of the compound's discovery. It was initially identified as a vasoconstrictor substance in blood serum - hence "serotonin", a serum agent affecting vascular tone. This agent was later chemically identified as 5-hydroxytryptamine (5-HT) and as the broad range of physiological roles were elucidated, 5-HT became the preferred name in the pharmacological field.

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