Purine
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Purine
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Chemical namePurine
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Chemical formulaC5H4N4
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Molecular mass120.11 g/mol
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Melting point214 °C
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CAS number120-73-0
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SMILESC1(NC=N2)=C2C=NC=N1
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Purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring.
Related Topics:
Heterocyclic - Aromatic - Organic compound - Pyrimidine - Imidazole
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The general term purines also refers to substituted purines and their tautomers. Two of the bases in nucleic acids, adenine and guanine, are purines. In DNA, these bases form hydrogen bonds with their complementary pyrimidines thymine and cytosine.
Related Topics:
Tautomer - Nucleic acid - Adenine - Guanine - DNA - Hydrogen bond - Complementary - Pyrimidine - Thymine - Cytosine
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In RNA, the complement of adenine is uracil (U) instead of thymine.
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These hydrogen bonding modes are for classical Watson-Crick base pairing. Other hydrogen bonding modes are seen in both DNA and RNA. Of significance, the additional 2'-hydroxyl group of the ribose moiety in RNA expands the configurations through which RNA can form hydrogen bonds.
Related Topics:
Watson-Crick base pair - DNA - RNA
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Other notable purines are xanthine, hypoxanthine, theobromine, caffeine and uric acid.
Related Topics:
Xanthine - Hypoxanthine - Theobromine - Caffeine - Uric acid
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Purines are biochemically significant as components of DNA and RNA, and are also found in a number of other important biomolecules, such as ATP, GTP, cyclic AMP, NADH, and coenzyme A.
Related Topics:
ATP - GTP - Cyclic AMP - NADH - Coenzyme A
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~ Table of Content ~
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