Protein folding

Protein folding is the process by which a protein structure assumes its functional shape or conformation. All protein molecules are heterogeneous unbranched chains of amino acids. By coiling and folding into a specific three-dimensional shape they are able to perform their biological function.

Related Topics:
Protein structure - Conformation - Heterogeneous - Amino acid

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The reverse of this process is protein denaturation, whereby a native protein is caused to lose its functional conformation, and become an amorphous, and non-functional amino acid chain. Denatured proteins may lose their solubility, and precipitate, becoming insoluble solids. In some cases, denaturation is reversible, and proteins may refold. In many other cases, however, denaturation is irreversible.

Related Topics:
Denaturation - Native - Precipitate - Insoluble

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