Osteogenesis imperfecta

Osteogenesis imperfecta (OI), commonly known as brittle bone disease, is a group of genetic bone disorders. People with OI do not produce enough good quality collagen to produce healthy, strong bones. Collagen is an important protein and without a good enough supply the bones are weak and break very easily.

Portrayal in popular culture

Osteogenesis imperfecta has been portrayed in the movie Unbreakable.

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