Necrotizing fasciitis

Necrotizing fasciitis is a serious but rare infection of the deeper layers of skin and subcutaneous tissues (fascia). Many types of bacteria can cause necrotizing fasciitis (eg. Group A streptococcus, Vibrio vulnificus, Clostridium perfringens, Bacteroides fragilis), of which Group A streptococcus is the most common cause.

Treatment

The diagnosis is confirmed by either blood cultures or aspiration of pus from tissue. Early medical treatment is critical. Treatment often includes intravenous penicillin, vancomycin and clindamycin. If necrotizing fasciitis is suspected, surgical exploration is always necessary, often resulting in aggressive debridement (removal of infected tissue). Limb amputation may be necessary.

Related Topics:
Blood culture - Pus - Tissue - Penicillin - Vancomycin - Clindamycin - Debridement - Amputation

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