Necrosis

: For chilean thrash metal band, check Necrosis (band)

Related Topics:
Chile - Thrash metal - Band - Necrosis (band)

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Necrosis (in Greek Νεκρός = Dead) is the name given to unprogrammed death of cells/living tissue (compare with apoptosis - programmed cell death). There are many causes of necrosis including injury, infection, cancer, infarction, inflammation and so on. Necrosis is caused by special enzymes that are released by lysosomes.

Related Topics:
Greek - Death - Tissue - Apoptosis - Programmed cell death - Injury - Infection - Cancer - Infarction - Inflammation - Enzyme - Lysosome

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There are four distinctive morphologic patterns of necrosis:

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• Coagulative necrosis - typically seen in hypoxic environments.. Cell outlines remain after cell death and can be observed by light microscopy (e.g. myocardial infarction, infarct of the spleen)
• Liquefactive necrosis - is associated with cellular destruction and pus formation (e.g. pneumonia)
• Caseous necrosis - is a mix of coagulative necrosis and liquefactive necrosis (e.g. tuberculosis)
• Fatty necrosis - results from the action of lipases on fatty tissues (e.g. acute pancreatitis)
• Fibrinoid necrosis - caused by immune-mediated vascular damage. It is marked by deposition of fibrin-like proteinaceous material in arterial walls, which appears smudgy and acidophilic on light microscopy.
 
Necrosis: See also ►