Multiple myeloma

Multiple myeloma (also known simply as myeloma or plasma cell myeloma, or as Kahler's disease after Otto Kahler) is a presently incurable hematological malignancy of plasma cells, the cells of the immune system that produce antibodies. Although it initially develops in the bone marrow, it spreads to the peripheral blood, lymph nodes and other organs. Its prognosis despite therapy is generally poor, and treatment may involve chemotherapy and bone marrow transplant.

Prognosis

Advanced age (age greater than 60), elevated lactate dehydrogenase, and decreased platelets are associated with a poorer prognosis. Cytogenetics may also be important for determining prognosis.

Related Topics:
Lactate dehydrogenase - Cytogenetics

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