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Melancholia


 

Melancholia (Greek μελαγχολια) was described as a distinct disease as early as the fifth and fourth centuries BC in the Hippocratic writings. It was characterized by "aversion to food, despondency, sleeplessness, irritability, restlessness," as well as the statement that "Grief and fear, when lingering, provoke melancholia". It is now generally believed that melancholia was the same phenomenon as what is now called clinical depression.

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