Kolbe-Schmitt reaction
The Kolbe-Schmitt reaction/Kolbe process (named after Adolph Wilhelm Hermann Kolbe and R. Schmitt) is a carboxylation chemical reaction that proceeds by heating sodium phenolate (the sodium salt of phenol) with carbon dioxide under pressure (100 atm, 125°C), then treating the product with sulfuric acid. The final product is an aromatic hydroxy acid of which salicylic acid (the precursor to aspirin) is a notable example.
Related Topics:
Adolph Wilhelm Hermann Kolbe - Carboxyl - Chemical reaction - Sodium - Salt - Phenol - Carbon dioxide - Atm - Sulfuric acid - Aromatic - Acid - Salicylic acid - Aspirin
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