Indole

History

Indole chemistry began to develop with the study of the dye indigo. This was converted to isatin and thence to oxindole. Then in 1866 Adolf von Baeyer reduced oxindole to indole using zinc dust, and in 1869 he proposed the formula for indole (left) that is accepted today.{{Ref|1}}

Related Topics:
Indigo - Isatin - Oxindole - 1866 - Adolf von Baeyer - Zinc

~ ~ ~ ~ ~ ~ ~ ~ ~ ~

Certain indole derivatives were important dyestuffs until the end of the 19th century. In the 1930s interest in indole intensified when it became known that the indole nucleus is present in many important alkaloids as well is in tryptophan and auxins, and it remains an active area of research today.

Related Topics:
1930s - Alkaloid - Tryptophan - Auxin

~ ~ ~ ~ ~ ~ ~ ~ ~ ~