Hydroboration-oxidation reaction

A hydroboration-oxidation reaction is an organic chemistry reaction used to add a hydroxyl group (OH-) and a hydrogen cation (H+) to an alkene via anti-Markovnikov addition. It adds with syn addition, leaving both added functional groups on the same side of the carbon-carbon double bond.

Related Topics:
Organic chemistry - Reaction - Hydroxyl - Hydrogen - Cation - Alkene - Anti-Markovnikov - Syn addition - Functional group - Carbon-carbon double bond

~ ~ ~ ~ ~ ~ ~ ~ ~ ~

The reaction involves first adding BH3 (B2H6) to an alkene and then adding peroxide and base (H2O2, OH-).

Related Topics:
Peroxide - Base

~ ~ ~ ~ ~ ~ ~ ~ ~ ~

The mechanism has the alkene double-bond attack BH3 to form a 4-member ring transition state. Peroxide is added to substitute the BH2 group with a hydroxyl group.

~ ~ ~ ~ ~ ~ ~ ~ ~ ~