Hepatitis C

Hepatitis C is a form of hepatitis (liver inflammation) caused by a virus, the Hepatitis C virus (HCV). Before the virus was discovered, in 1989, the syndrome was initially referred to as a "non-A-non-B hepatitis". In about 15% of cases, hepatitis C infection is acute, meaning it is cleared spontaneously by the body and there are no long-term consequences. Unfortunately, in the majority of cases (85%), the infection becomes chronic and may damage the liver over many years.

Treatment

Treatment is mainly based on interferon alpha (IFNα), combined with other drugs; though this action does not guarantee results. Currently, the preferred treatment is pegylated interferon together with ribavirin. Studies have shown sustained cure rates of 75% or better in people with genotypes 2 or 3 HCV (which is easier to treat) and about 50% in those with genotype 1.

Related Topics:
Interferon alpha - Pegylated - Ribavirin

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Individuals with Hepatitis C should be vaccinated for Hepatitis A and B if they have not yet been exposed to these viruses.

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It is well known that alcohol makes HCV associated liver disease progress faster, and makes interferon treatment less effective.

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