G protein


 
 

G-proteins, short for guanine nucleotide binding proteins, are a family of proteins involved in second messenger cascades. They are so-called because of their signaling mechanism, which uses the exchange of

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Guanosine diphosphate (GDP) for Guanosine triphosphate (GTP) as a molecular "switch" to allow or inhibit biochemical reactions inside the cell. Alfred Gilman and Martin Rodbell were awarded the Nobel Prize in Physiology or Medicine in 1994 for their discovery and research on G-proteins.

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Protein: A protein (in Greek πρωτεϊνη = first thread) is a complex, high-molecular-weight organic compound that consists of amino acids joined by peptide bonds. Proteins are essential to the structure and function of all living cells and viruses....

Second messenger: In biology, second messengers are low-weight diffusible molecules that are used in signal transduction to relay a signal within a cell. They are synthesized or released by specific enzymatic reactions, usually as a result of an external signal that was received by a...

Guanosine triphosphate: Guanosine triphosphate (GTP) is also known as guanosine-5'-triphosphate and G3P. Biochemically, GTP is 9-?-D-ribofuranosylguanine-5'-triphosphate or, equivalently, 9-?-D-ribofuranosyl-2-amino-6-oxo-purine-5'-triphosphate. GTP is a purine nucleotide that is incorporated into the growing RNA chain d...


G protein related Images and Photos (experimental)

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~ Table of Content ~

Introduction
General properties
Receptor-activated G-proteins
References
 
FR: Protéine G


 

~ Related Subjects ~

Cell (2) - Molecule (1) - Signal transduction (1) - Diffusible (1) - Cells (1) - Virus (1) - Biology (1) - Enzymatic (1) - RNA (1) - RNA synthesis (1) - Protein synthesis (1) - Biochemically (1) - Purine (1) - Nucleotide (1) - Guanosine triphosphate (1) -
 

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