Epinephrine

:For the Deftones' album; see Adrenaline (album).

Pharmacology

Epinephrine's actions are mediated through adrenergic receptors (sometimes referred to as adrenoceptors).

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It binds to α1 receptors of liver cells, which activate inositol-phospholipid signaling pathway, signaling the phosphorylation of insulin, leading to reduced ability of insulin to bind to its receptors.

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Epinephrine also activates β-adrenergic receptors of the liver and muscle cells, which activates the adenylate cyclase signaling pathway, which will in turn increase glycogenolysis.

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