DNA microarray

A DNA microarray is a collection of microscopic DNA spots attached to a solid surface, such as glass, plastic or silicon chip forming an array. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously. The affixed DNA segments are known as reporters, thousands of which can be used in a single DNA microarray. Microarray technology evolved from Southern Blotting, where fragmented DNA is attached to a substrate and then probed with a known gene or fragment. Measuring gene expression using microarrays is relevant to many areas of biology and medicine, such as studying treatments, disease and developmental stages.

Related Topics:
DNA - Glass - Plastic - Silicon chip - Array - Genes - Southern Blotting - Substrate - Gene expression - Biology - Medicine - Disease

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