Dimethyltryptamine

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Dimethyltryptamine, also known as DMT or N,N-dimethyltryptamine, is an indole, similar in structure to the neurotransmitter serotonin, created during normal metabolism in low amounts by the human body. Pure DMT at room temperature is a colorless waxy or crystalline solid. DMT was first chemically synthesized in 1931. It also occurs naturally in many species of plants. DMT-containing plants are used in several South American shamanic practices. It is one of the main active constituents of snuffs like yopo and of the potion ayahuasca.

Related Topics:
Indole - Neurotransmitter - Serotonin - Chemically synthesized - 1931 - Plants - South America - Shaman - Yopo - Ayahuasca

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DMT is not orally active unless combined with a monoamine oxidase inhibitor (MAOI), such as harmaline. Without an active MAOI, the body quickly metabolizes DMT, and therefore has no significant hallucinogenic effect.

Related Topics:
Monoamine oxidase inhibitor - Harmaline

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