Chronic myelogenous leukemia

Chronic myelogenous leukemia (or CML) is a form of chronic leukemia characterised by increased production of myeloid cells in the bone marrow. The overwhelming majority is due to a characteristic chromosomal translocation termed the Philadelphia chromosome. It is traditionally treated with chemotherapy, interferon and bone marrow transplantation, although a specific inhibitor (imatinib mesylate) has radically changed the management.

Related Topics:
Leukemia - Bone marrow - Chromosomal translocation - Philadelphia chromosome - Chemotherapy - Interferon - Bone marrow transplantation - Imatinib mesylate

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