Chloramphenicol

Chloramphenicol is an antibiotic that was derived from the bacterium Streptomyces venezuelae and is now produced synthetically. Chloramphenicol is effective against a wide variety of microorganisms, but due to serious side-effects (e.g., damage to the bone marrow, including aplastic anemia) in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., typhoid fever).

Related Topics:
Antibiotic - Bacterium - Streptomyces venezuelae - Bone marrow - Aplastic anemia - Infection - Typhoid fever

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Regardless of serious side-effects, the WHO advocates its use in many third world countries for pediatric treatment in the absence of cheaper alternatives.

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It is used in treatment of cholera, as it destroys the vibrios and decreases the diarrhea. It is effective against tetracycline-resistant vibrios.

Related Topics:
Cholera - Vibrio - Diarrhea - Tetracycline

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It is also used in eye drops or ointment to treat bacterial conjunctivitis.

Related Topics:
Eye drop - Ointment - Conjunctivitis

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C11H12Cl2N2O5 Chloramphenicol MW=323.13

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(2,2-Dichlor-N-acetamide) Image in the PD.

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