Chloracne

Chloracne is an acne-like eruption of blackheads, cysts, and pustules associated with over-exposure to certain halogenic aromatic hydrocarbons, such as chlorinated dioxins and dibenzofurans. The lesions are most frequently found on the cheeks, behind the ears, in the armpits and groin region.

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The condition was first described in German industrial workers in 1897 by Von Bettman, and was initially believed to be caused by exposure to toxic chlorine (hence the name "chloracne"). It was only in the mid-1950s that chloracne was associated with aromatic hydrocarbons. The substances that may cause chloracne are now collectively known as "chloracnegens".

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Chloracne is particularly linked to toxic exposure to dioxins (byproducts of many chemical processes, including the manufacture of herbicides such as Agent Orange) — so much so that it is considered a clinical sign of dioxin exposure. The severity and onset of chloracne may follow a typical asymptotic dose response curve.

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Acne: Acne is an inflammatory disease of the skin, caused by changes in the pilosebaceous units (skin structures consisting of a hair follicle and its associated sebaceous gland). The most common form of acne is known as "acne vulgaris", which means common acne. Excessive secretion of oils from the glands...

Blackhead: Blackhead may either link to:...

Cyst: A cyst is a closed sac having a distinct membrane and developing abnormally in a cavity or structure of the body. They can occur as a result of a developmental error in the embryo during pregnancy or they can be caused by infections. However, they sometimes arise spontaneously with no apparent cause...