Charleston, South Carolina

Interstates and major highways in Charleston

• Interstate 26 is the VIA Freeway in the Charleston-North Charleston Metropolitan Area; it ends at The Septima Clark Expressway downtown Charleston.
• Interstate 526, or the Mark Clark Expressway, forms a half-circle around the city. It may soon make a complete circle and become Interstate 426
• U.S. Highway 17 is the Septima Clark Expressway Downtown and becomes Savannah Highway after it crosses the Ashley River. This highway runs through the middle of the city.
• U.S. Highway 52 is Market Street and its spur is Morisson Drive, which becomes East Bay Street after leaving the Eastside.
• U.S. Highway 78 is Rivers Avenue in North Charleston, which then becomes King Street in downtown Charleston.