Charles Nicolle

Dr. Charles Jules Henry Nicolle (September 21, 1866 - February 28, 1936) was a bacteriologist who earned the 1928 Nobel Prize in Medicine for his identification of lice as the transmitter of epidemic typhus.

Attempt at a Vaccine

Dr. Nicolle surmised that he could make a simple vaccine by crushing up the lice and mixing it with blood serum from recovered patients. He first tried this vaccine on himself, and when he stayed healthy he tried it on a few children (because of their better immune systems), who developed typhus but recovered.

Related Topics:
Vaccine - Blood serum

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He did not succeed in his effort to develop a practical vaccine. The next step would be taken by Rudolf Weigl in 1930.

Related Topics:
Rudolf Weigl - 1930

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