Aziridine

Aziridines are a group of organic compounds sharing the azirine functional group which is a three membered heterocycle with one amine group and two methylene groups 1,2. The parent compound of the aziridines is called aziridine with molecular formula C2H5N.

~ ~ ~ ~ ~ ~ ~ ~ ~ ~

~ ~ ~ ~ ~ ~ ~ ~ ~ ~

The bond angles in azirine are around 60? which is considerable shorter than the bond angle of 109.5? found in ordinary hydrocarbons and this results in angle strain just like in the comparable cyclopropane and oxirane molecules. Bonding is this type of compound can be explained by invoking a banana bond model. Aziridine is less basic than acyclic aliphatic amines with a pKa of 7.9 for the conjugate acid due to inreased s character of the nitrogen free electron pair. Increased angle strain in aziridine is also responsible for increased barrier for nitrogen inversion. This barrier is high enough for the isolation of separate invertomers for instance the cis and trans invertomers of N-chloro-methylazirine.

Organic compound: An organic compound is any member of a large class of chemical compounds whose molecules contain carbon, with exception of carbides, carbonates, carbon oxides and gases containing carbon. The study of organic compounds is termed organic chemistry. Many of these compounds, such as proteins, fats, and...

Functional group: In ecology functional groups are collections of organisms based on morphological, physiological, behavioral, biochemical, or environmental responses or on trophic criteria....

Heterocycle: Heterocycles are organic chemical structures containing non-carbon elements. Epoxides (oxiranes), aziridines, pyridines, thiophenes, many other structural classes are heterocyclic....